A SYSTEMATIC REVIEW OF GENETIC FACTORS INVOLVED IN CARDIOVASCULAR DISORDERS
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Date
2022-06-16
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Department of biotechnology, KCW Lahore.
Abstract
Background:
Cardiovascular disorder is the leading causality of death around the world.
Cardiovascular disorders have multiple environmental and genetic risk factors
contributing towards different types of CVD. This study aimed to investigate most
prevalent type of CVD among Pakistani population.
Methods:
Total 50 clinical reports were collected from patients by visiting different private and
public health institutes in Lahore, Pakistan. The thorough literature review was
performed by using different databases including Google scholar and PubMed to
analyze different types of cardiovascular diseases. SPSS software version 16.0 was
used to analyze the results.
Results:
Our results showed that Rheumatic heart disease is the most usual type of heart
disease in Pakistan (34.0%) whereas; Left ventricular systolic function (LVF) and
Patent ductus arteriosus (PDA) are the least reported cases (2.0%)
Conclusion:
Our findings suggests that broad clinical and genetic spectrum of cardiovascular
disorders in Pakistan.
Description
Keywords
Genetic elucidation, Cardiovascular disorders, Epigenetics, Mutation, Novel variants