Browsing by Author "ZARA BASHIR"

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    SYNTHESIS OF IONIC LIQUIDS AND THEIR IN-VIVO AND IN-VITRO TOXICOLOGICAL ASSA
    (DEPARTMENT OF ZOOLOGY KINNAIRD COLLEGE FOR WOMEN UNIVERSITY LAHORE,, 2023-06-15) ZARA BASHIR
    Deep eutectic solvents belong to the class of ionic liquids. They are called as “Designer solvents” because we can mold or change them according to our requirements. The synthesis of Ionic liquid (ILs) and them in-vivo and in-vitro toxicological activities were the main goals of this study. An ammonium-based salt tetrahexyl ammonium bromide (THAB) was taken as a hydrogen bond acceptor and decanoic acid (DA) was taken as a hydrogen bond donor to synthesize deep eutectic solvent. Both components were heated at 80oC for 2 hours. A homogenous solution was obtained which was labelled as S13. The pure and diluted form of solvent was applied to bacteria, fungi and fish to test its toxicity. The solvent shows both positive and negative toxic effects on test organisms. In bacteria 10-3 didn’t show any zone of inhibition on S.aureus and in E.coli on 10-2 it didn’t show any zone of inhibition. DES was applied to pre cultured plates of A.niger an inhibition ring showed up after incubation and zero inhibition on cultured plates of A.niger. In full test in fishes, all dilutions except 10-5 resulted in mortalities
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    SYNTHESIS OF IONIC LIQUIDS AND THEIR IN-VIVO AND IN-VITRO TOXICOLOGICAL ASSAY
    (DEPARTMENT OF ZOOLOGY KINNAIRD COLLEGE FOR WOMEN UNIVERSITY LAHORE,, 2023-06-15) ZARA BASHIR
    Deep eutectic solvents belong to the class of ionic liquids. They are called as “Designer solvents” because we can mold or change them according to our requirements. The synthesis of Ionic liquid (ILs) and them in-vivo and in-vitro toxicological activities were the main goals of this study. An ammonium-based salt tetrahexyl ammonium bromide (THAB) was taken as a hydrogen bond acceptor and decanoic acid (DA) was taken as a hydrogen bond donor to synthesize deep eutectic solvent. Both components were heated at 80oC for 2 hours. A homogenous solution was obtained which was labelled as S13. The pure and diluted form of solvent was applied to bacteria, fungi and fish to test its toxicity. The solvent shows both positive and negative toxic effects on test organisms. In bacteria 10-3 didn’t show any zone of inhibition on S.aureus and in E.coli on 10-2 it didn’t show any zone of inhibition. DES was applied to pre cultured plates of A.niger an inhibition ring showed up after incubation and zero inhibition on cultured plates of A.niger. In full test in fishes, all dilutions except 10-5 resulted in mortalities.