ANTIFUNGAL AND INJURY REGENERATION POTENTIAL OF GREEN TEA

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2023-06-15

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DEPARTMENT OF ZOOLOGY KINNAIRD COLLEGE FOR WOMEN UNIVERSITY LAHORE,

Abstract

Green tea has beneficial effects on human health including anticarcinogenic, antiviral, antibacterial and antifungal activity. The purpose of this study is to evaluate the wound healing and antifungal ability of green tea plants in acid burn rats and Candida albican. The antifungal activities were done by ditch plate method. The antifungal potential of green tea extract on Candida albican established remarkably positive results by demonstrating the inhibitory zone at a level of 40 ul. Biochemical assays such as antioxidant tests were conducted. ELISA protocol was used to evaluate the angiogenesis and the antibodies used were Annexin-V and VEGF. Camellia Sinensis plant extract showed remarkable wound healing capacity with elevated VEGF levels at a dosage of 100 mg/ml and decreases apoptosis level by using the same concentration. The ability of green tea extract to treat wounds was also proven by the histopathological examination. The wound index was measured to study the wound healing power of green tea extract and the results were significant. The study depicts that wound healing was observed after green tea plant treatment.

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