ANTICANCER AND SKIN REPAIR POTENTIAL OF GUAR GUM
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Date
2023-06-15
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DEPARTMENT OF ZOOLOGY KINNAIRD COLLEGE FOR WOMEN UNIVERSITY LAHORE,
Abstract
Guar gum is one of the medicinal plants that has been used for various diseases treatments.
The purpose of this study is to assess the guar gum plant's capacity to wound healing
process and prevent cancer in acid-burned rats. The wound healing capacity of Guar gum
extract at different doses (50 and 100 mg/ml) was estimated by using different biochemical
experiments. Wound index measurement was done to study wound healing ability of guar
gum powder aqueous extract and results were significant indicating the wound healing
ability of plant. The maximum potential of healing was observed at 100 mg/ml dose that
was (2.2±0.24). MTT assay calculations were used to determine the anticancer
effectiveness. The angiogenesis was assessed using the ELISA procedure and antibodies
against VEGF (2.6±0.052) and Annexin (1.1±0.033). Biochemical analysis shows that
wound become better after treatment with guar gum powder. The high dose level of guar
gum plant powder treatment in the current study suggests that it has both anticancer and
wound-healing properties